International News: Every day our soul fights millions of yes-man and viruses. The immune system protects us. But sometimes it attacks its own organs. This condition is tabbed autoimmune disease. Three Nobel laureate scientists solved the mystery of why the immune system does not fight itself. In 1995, Japanese scientist Shimon Sakaguchi proved that the protection of the immune system does not lie only in an organ tabbed thymus. He discovered that a new type of cell, tabbed regulatory T cell, protects the soul from itself.
Contributions by Brunckow and Ramsdell
In 2001, Mary Brunckow and Fred Ramsdell discovered a specific gene. They found that if this gene, tabbed "Foxp3," becomes damaged, the immune system becomes impaired. Experiments conducted on mice revealed that this gene defect causes serious illness. These scientists later discovered that if this gene becomes damaged in humans, it causes a dangerous disease tabbed IPEX. In this condition, children suffer from severe autoimmune problems as soon as they are born. Its treatment is extremely difficult.
The relationship between genes and cells
In 2003, Sakaguchi proved that this Foxp3 gene is responsible for the insemination of regulatory T cells. This ways that without this gene, these cells cannot be formed, and the immune system begins to wade itself. This discovery gave doctors new hope. Now, new drugs are stuff ripened to treat autoimmune diseases like diabetes, arthritis, and cancer. This will moreover be of unconfined goody to organ transplant patients.
Hope for patients virtually the world
The throne of the Nobel Committee said that this discovery explains why not everyone develops a serious autoimmune disease. In the future, this discovery could bring relief to millions of patients and save many lives. Doctors believe these findings will guide largest treatment options for chronic illnesses. New therapies are once stuff tested in clinical trials worldwide. Patients suffering from autoimmune disorders may soon get longer-lasting relief. This Nobel-winning work has opened a fresh installment in medical science.
